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Novel dopamine D2 receptor ligands for Parkinson’s disease & schizophrenia
Dopamine is a catecholamine neurotransmitter that mediates physiological functions in the central and peripheral nervous systems. Binding of dopamine to the dopamine D2 receptor elicits intracellular signaling implicated in various neurological disorders such as Parkinson’s disease (PD) and schizophrenia. Drugs targeting the dopamine D2 receptor...
Published: 3/4/2024
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Inventor(s): Thomas Keck, Chun Wu
Keywords(s): Compounds, Dopamine D2, Neurological, Parkinson Disease, Schizophrenia, Therapeutic, Treatment
Category(s): Human Health Care > Therapeutics
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Phenolic Epoxy Methacrylate Monomers Derived from Renewable Sources and Their Method of Preparation
TechnologyBisphenol-A is a chemical produced in large quantities since the 1960s for use primarily in the production of polycarbonate plastics and epoxy resins. Polycarbonate plastics and epoxy resins are used in a number of applications including food and drink packaging and to coat products, respectively. In 2010, the United States Food and Drug Administration...
Published: 2/14/2024
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Inventor(s): Joseph Stanzione, Alexander Bassett, John La Scala
Keywords(s): Biomaterials, Compounds, Manufacturing , Plastics, Polymers, Resin
Category(s): Engineering > Materials
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Targeting Podoplanin to Combat Cancer
Sentrimed® is launching its first product, MASL®, to treat and prevent cancer and arthritis. Our technology is protected by issued patents and proprietary technology tailored to combat cancer and inflammatory diseases by targeting a unique receptor, called podoplanin (PDPN), which is expressed by cancer and inflammatory cells. We have received...
Published: 2/16/2024
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Inventor(s): Gary Goldberg, Yongquan Shen
Keywords(s): Cancer, Compounds, Therapeutic
Category(s): Human Health Care > Therapeutics
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Bio-based Phenolic-containing Polymers
TechnologyBisphenol-A is a chemical produced in large quantities since the 1960s for use primarily in the production of polycarbonate plastics and epoxy resins. Polycarbonate plastics and epoxy resins are used in a number of applications including food and drink packaging and to coat products, respectively. In 2010, the United States Food and Drug Administration...
Published: 2/14/2024
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Inventor(s): Craig Paquette, John La Scala, Joshua Sadler, Alexander Bassett, Joseph Stanzione, Palmese Giuseppe
Keywords(s): Biomaterials, Compounds, Manufacturing , Plastics, Polymers, Resin
Category(s): Engineering > Materials
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Bio-based Multi-aromatic Compounds
TechnologyIntermolecular condensation is a chemical reaction in which two or more molecules combine to form a larger molecule, with the simultaneous loss of one or more smaller molecules, such as water, methanol, ethanol, acetic acid, or hydrogen chloride. One of the most common examples of an intermolecular condensation reaction is the formation of...
Published: 2/8/2024
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Inventor(s): Alexander Bassett, Joseph Stanzione, John La Scala, Joshua Sadler, Owen Stecca
Keywords(s): Biomaterials, Compounds, Manufacturing , Plastics, Plastics, Plastics, Polymers, Resin
Category(s): Engineering > Materials
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