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Novel hasubanan-based analgesics
There are three main medication alternatives for use in treating opioid addiction; methadone, buprenorphine, and naltrexone which can be used separately or in combination (e.g., buprenorphine and naltrexone). All three medications are FDA approved and can reduce opioid cravings helping to sever the ties between opioid use and situational/emotional triggers....
Published: 2/5/2024   |   Inventor(s): Thomas Keck, Gustavo Moura-Letts
Keywords(s): Addiction, Neurological disorders, Therapeutic
Category(s): Human Health Care > Therapeutics
Vaccine for the Treatment of Cocaine Addiction and Relapse
Cocaine is the second most trafficked illegal substance in the world with more than 756 metric tons seized every year from authorities. In the United States, over 35 million people over the age of 12 have reported using cocaine, while being the most frequent illegal drugs reported by emergency rooms. Its popularity is due to its highly addictive nature...
Published: 2/9/2024   |   Inventor(s): Thomas Keck, Christopher Lowry
Keywords(s): Addiction, Cocaine, Inflammation, PTSD, Vaccine
Category(s): Human Health Care > Therapeutics
Novel dopamine D2 receptor ligands for Parkinson’s disease & schizophrenia
Dopamine is a catecholamine neurotransmitter that mediates physiological functions in the central and peripheral nervous systems. Binding of dopamine to the dopamine D2 receptor elicits intracellular signaling implicated in various neurological disorders such as Parkinson’s disease (PD) and schizophrenia. Drugs targeting the dopamine D2 receptor...
Published: 3/4/2024   |   Inventor(s): Thomas Keck, Chun Wu
Keywords(s): Compounds, Dopamine D2, Neurological, Parkinson Disease, Schizophrenia, Therapeutic, Treatment
Category(s): Human Health Care > Therapeutics