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Multi-material 3D bioprinter for use in drug testing/screening supporting cancer drug discovery.
Cancer testing/screening procedures used in developing new drug therapies take years and are founded on the use of 2D cell cultures and animal models prior to human trials. This pathway is not always representative of how a drug will perform in humans since 2D technology cannot print multi-material bio-cell structures for evaluating new drug performance....
Published: 3/7/2024   |   Inventor(s): Amir Miri Ramsheh
Keywords(s): 3D, Cancer, Drug Screening, Hydrogels, Medical Devices
Category(s): Human Health Care > Biomarkers, Diagnosis and Detection, Research Tools
A Method for Detecting Radiological Progression in Cancer Surveillance
Diagnostic medical imaging technologies such as Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are noninvasive procedures used to acquire high-resolution images of organs/tissues in the body. These technologies provide valuable information for identifying tissue damage, disease diagnosis, and delivery of radiation therapy. Both of these...
Published: 2/5/2024   |   Inventor(s): Nidhal Bouaynaya, Ghulam Rasool, Hassan Fathallah-Shaykh
Keywords(s): Cancer, Imaging, Machine Learning, MRI, Quantification, Radiology, Software, Surveillance
Category(s): Software, Human Health Care > Biomarkers, Diagnosis and Detection
Autoantibody Profiles and Protein Microarrays as a Multi-Diagnostic Platform for Simultaneous Early Detection and Diagnosis of Numerous Cancers
TechnologyEarly detection of cancer is essential for successful disease management. In response, considerable research has gone into the development of cancer diagnostics that detect cancer even before the manifestation of clinical symptoms. Biomarkers, in particular, have proven not only useful in following the course of cancer, but also for evaluating...
Published: 3/6/2024   |   Inventor(s): Robert Nagele, Eric Nagele
Keywords(s): Antibody, Cancer, Diagnostics, Microarray
Category(s): Human Health Care > Biomarkers, Diagnosis and Detection
Cyclin C and its role in cancer and cancer therapeutics
Cancer is a leading cause of death worldwide with more than 14 million new patients diagnosed and almost 9 million deaths every year. Despite increasing survival rates over the past few decades, current treatments such as radiation, chemotherapy, targeted therapies and new immunotherapies still fail in large subsets of patients. Mounting drug resistance...
Published: 3/13/2024   |   Inventor(s): Randy Strich, Katrina Cooper
Keywords(s): Apoptosis, Cancer, Chemotherapy, Cyclin C, Radiation, Synergy, Therapeutic
Category(s): Human Health Care > Therapeutics
Targeting Podoplanin to Combat Cancer
Sentrimed® is launching its first product, MASL®, to treat and prevent cancer and arthritis. Our technology is protected by issued patents and proprietary technology tailored to combat cancer and inflammatory diseases by targeting a unique receptor, called podoplanin (PDPN), which is expressed by cancer and inflammatory cells. We have received...
Published: 2/16/2024   |   Inventor(s): Gary Goldberg, Yongquan Shen
Keywords(s): Cancer, Compounds, Therapeutic
Category(s): Human Health Care > Therapeutics