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Autoantibody Profiles and Protein Microarrays as a Multi-Diagnostic Platform for Simultaneous Early Detection and Diagnosis of Numerous Cancers
TechnologyEarly detection of cancer is essential for successful disease management. In response, considerable research has gone into the development of cancer diagnostics that detect cancer even before the manifestation of clinical symptoms. Biomarkers, in particular, have proven not only useful in following the course of cancer, but also for evaluating...
Published: 3/6/2024   |   Inventor(s): Robert Nagele, Eric Nagele
Keywords(s): Antibody, Cancer, Diagnostics, Microarray
Category(s): Human Health Care > Biomarkers, Diagnosis and Detection
A new serum-based diagnostic for the detection of substance abuse and other addictive disorders
The proposed technology is a novel approach to a serum biomarker for substance abuse disorder based on the positive correlation between plasma S100B protein levels and addiction. It is proposed that the expression levels of the S100B protein will serve as an indicator of the process of addiction and decision-making. The changes may be detectable in...
Published: 2/13/2024   |   Inventor(s): Venkat Venkataraman, Richard Jermyn, Robert Steer
Keywords(s): Addiction, Biomarkers, Diagnostics, Substance Abuse
Category(s): Human Health Care > Biomarkers, Diagnosis and Detection
Artificial Intelligent Readings of Imaging Data for Coronary Artery Disease
Health care spending in the United States accounts for nearly 20% of the gross domestic product. In the changing health care environment, health systems, hospitals, and health care providers must focus on improving efficiency to meet an increasing demand for high-quality, low-cost health care. In response to this growing need to reduce costs, application...
Published: 3/5/2024   |   Inventor(s): Bo (Beth) Sun
Keywords(s): Assesments, Cardiology, Diagnostics, Heart Disease, Imaging, Software, Surgery
Category(s): Software
A Sensitive and Accurate Diagnostic for Periprosthetic Joint Infection
Periprosthetic joint infection (PJI) is a devastating and costly complication following total hip replacement and total knee replacement. With the increase in the number of total joint replacements procedures performed annually, the number of complications involving revision surgery are also on the rise. PJI often results in implant failure and places...
Published: 3/6/2024   |   Inventor(s): Alisina Shahi
Keywords(s): Assesments, Diagnostics, Hip Replacement, Implant, Infection, Joint, Knee Replacement, Orthopedics
Category(s): Human Health Care > Medical Devices, Human Health Care > Biomarkers, Diagnosis and Detection
A novel technique related to identifying and treating oxidative stress disorders
BackgroundThe diagnosis of oxidative stress related disorders plays a critical role in developing therapeutic options for the treatment of these diseases, including autism. Docosahexaenoic acid (DHA) is the major brain lipid and the parent molecule for a large number of intracellular and extracellular messengers. Oxidation of DHA gives rise to a series...
Published: 3/6/2024   |   Inventor(s): Bernd Spur, Thomas Stein, George Lambert, Sue Ming, Ana Rodriguez
Keywords(s): ADHD, Autism, Biomarkers, DHA Metabolism, Diagnostics, Stress Disorder, Urine Test
Category(s): Human Health Care > Biomarkers, Diagnosis and Detection