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Automatic Aortic Aneurysm Detection System through Deep-Learning
An aortic aneurysm is a bulge that occurs in the aorta wall, which carries blood from the heart to the rest of the body. In 2019, aortic aneurysms caused more than 9,000 deaths, with about 60% affecting men. Smoking accounts for the condition's leading risk factor and leads to 75% of all aortic aneurysms. Unfortunately, current diagnostic tools...
Published: 2/5/2024
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Inventor(s): Li Yupeng, Hieu Nguyen
Keywords(s): Aneurysm, CT (Computed Tomography), Detection, Machine Learning
Category(s): Engineering, Human Health Care > Biomarkers, Diagnosis and Detection, Software
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Self-forming in vivo dosimeter for radiation therapy verification
Radiation therapy (RT) is one of the most common treatment modalities for cancer and is used in approximately 50% of all treatment plans. It's estimated that RT is responsible for more than 3.5 million successful treatment outcomes along with another 3.5 million for palliative care. Although RT effectively kills cancer, it can cause damage...
Published: 2/5/2024
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Inventor(s): Sebastián Vega, Kirstene Gultian, Leonard Kim, Irina Malajovich, Geoffrey Ibbott
Keywords(s): Dosimetry, Drug Delivery, Hydrogels, Radiation Therapy, Radiotherapy
Category(s): Engineering, Human Health Care > Biomarkers, Diagnosis and Detection
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A non-electronic reference implant for detection of implant loosening
after joint replacement surgery
Joint replacement is an effective surgical intervention for some joint diseases. Implant loosening is a disabling condition that can affect patients after joint replacement surgery. Unfortunately, subtle progression of tissue deterioration around the implant remains a major challenge, because signs and symptoms may not be clinically apparent until...
Published: 3/5/2024
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Inventor(s): Hanna Dietrich, Joseph DiFranceisco, Miguel Isaga, Luke Austin, Erik Brewer, Hamid Seyyedhosseinzadeh, Mary Staehle, Ann DiGuglielmo
Keywords(s): Arthroplasty, Implant, Joint, Radiography, Replacement , Surgery
Category(s): Human Health Care > Medical Devices, Human Health Care > Biomarkers, Diagnosis and Detection
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Multi-material 3D bioprinter for use in drug testing/screening supporting cancer drug discovery.
Cancer testing/screening procedures used in developing new drug therapies take years and are founded on the use of 2D cell cultures and animal models prior to human trials. This pathway is not always representative of how a drug will perform in humans since 2D technology cannot print multi-material bio-cell structures for evaluating new drug performance....
Published: 3/7/2024
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Inventor(s): Amir Miri Ramsheh
Keywords(s): 3D, Cancer, Drug Screening, Hydrogels, Medical Devices
Category(s): Human Health Care > Biomarkers, Diagnosis and Detection, Research Tools
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A Method for Detecting Radiological Progression in Cancer Surveillance
Diagnostic medical imaging technologies such as Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are noninvasive procedures used to acquire high-resolution images of organs/tissues in the body. These technologies provide valuable information for identifying tissue damage, disease diagnosis, and delivery of radiation therapy. Both of these...
Published: 2/5/2024
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Inventor(s): Nidhal Bouaynaya, Ghulam Rasool, Hassan Fathallah-Shaykh
Keywords(s): Cancer, Imaging, Machine Learning, MRI, Quantification, Radiology, Software, Surveillance
Category(s): Software, Human Health Care > Biomarkers, Diagnosis and Detection
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Compositions and Methods to Treat Inflammatory Joint Disease
TechnologyInflammatory joint disease is an autoimmune condition that afflicts more than 54 million adults in the United States. It’s commonly characterized by joints that exhibit pain, stiffness, and redness that ultimately leads to severe disability and premature death. Incidence of the disease is rapidly growing due to rising obesity rates,...
Published: 3/6/2024
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Inventor(s): Paula Carpintero Fernandez, Maria Mayan Santos, Francisco Blanco Garcia, Gary Goldberg
Keywords(s): Autoimmune/Immunology, Disease, Inflammatory, Joint, Obesity, Protein
Category(s): Human Health Care > Therapeutics, Human Health Care > Biomarkers, Diagnosis and Detection
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Autoantibody Profiles and Protein Microarrays as a Multi-Diagnostic Platform for Simultaneous Early Detection and Diagnosis of Numerous Cancers
TechnologyEarly detection of cancer is essential for successful disease management. In response, considerable research has gone into the development of cancer diagnostics that detect cancer even before the manifestation of clinical symptoms. Biomarkers, in particular, have proven not only useful in following the course of cancer, but also for evaluating...
Published: 3/6/2024
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Inventor(s): Robert Nagele, Eric Nagele
Keywords(s): Antibody, Cancer, Diagnostics, Microarray
Category(s): Human Health Care > Biomarkers, Diagnosis and Detection
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A new serum-based diagnostic for the detection of substance abuse and other
addictive disorders
The proposed technology is a novel approach to a serum biomarker for substance abuse disorder based on the positive correlation between plasma S100B protein levels and addiction. It is proposed that the expression levels of the S100B protein will serve as an indicator of the process of addiction and decision-making. The changes may be detectable in...
Published: 2/13/2024
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Inventor(s): Venkat Venkataraman, Richard Jermyn, Robert Steer
Keywords(s): Addiction, Biomarkers, Diagnostics, Substance Abuse
Category(s): Human Health Care > Biomarkers, Diagnosis and Detection
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A Sensitive and Accurate Diagnostic for Periprosthetic Joint Infection
Periprosthetic joint infection (PJI) is a devastating and costly complication following total hip replacement and total knee replacement. With the increase in the number of total joint replacements procedures performed annually, the number of complications involving revision surgery are also on the rise. PJI often results in implant failure and places...
Published: 3/6/2024
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Inventor(s): Alisina Shahi
Keywords(s): Assesments, Diagnostics, Hip Replacement, Implant, Infection, Joint, Knee Replacement, Orthopedics
Category(s): Human Health Care > Medical Devices, Human Health Care > Biomarkers, Diagnosis and Detection
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An innovative and non-invasive method for early detection and diagnosis of skin disorders
BackgroundSkin disease is one of the leading causes of global disease burden, affecting millions worldwide. There are at least 15 categories of skin diseases, with acne, fungal skin disease, and skin and subcutaneous disease being the most prevalent. Skin diseases are not only a detriment to the skin and quality of life, but also spread over time. It...
Published: 3/6/2024
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Inventor(s): Ben Wu, Gina (Ying) Tang, Xiao Hu
Keywords(s): 3D, Diagnosis, Fluorescence, Imaging, Microscopy , Noninvasive, Skin Disease
Category(s): Human Health Care > Biomarkers, Diagnosis and Detection, Research Tools
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