|
New RNA-based Biomarker Discovery and Diagnostics
Brief Description
A molecular diagnostic platform that enables characterization of cellular stress and damage. This technology may be applied to a broad range of clinical settings, from assessing the efficacy of cancer therapies to detecting inflammatory and autoimmune disorders, ischemia/reperfusion injury, and toxic environmental exposures.
Problem
There...
Published: 1/13/2026
|
Inventor(s): Dimitri Pestov, Ekaterina Kashkina
Keywords(s):
Category(s): Engineering
|
|
Improved preclinical models for drug discovery using vascularized organoids
Brief Description
We have developed a process to 3D-print hydrogels that can be spatially patterned with peptide motifs to anchor vascularized organoids and facilitate intraluminal perfusion: providing a bridge between traditional chip-based models and tissue specific organoids.
Problem
Organoids are generally cultured in rocker environments or other...
Published: 1/13/2026
|
Inventor(s): Peter Galie, Louis Paone
Keywords(s):
Category(s): Engineering
|
|
Machine Learning-Enhanced Neurocognitive Assessment in Primary Healthcare Settings
Brief Description
The Rowan Assessment of Visual Memory and Attention (RAMA) is an easy-to-administer, non-invasive iPad-based assessment composed of four well-tolerated, non-verbal neuropsychological tests. Employed in research underway at leading hospitals, the RAMA tests generate data that powers a machine learning algorithm for highly accurate...
Published: 1/28/2026
|
Inventor(s): Ganesh Baliga, David Libon, Mary Kerwin, Rod Swenson
Keywords(s):
Category(s): Engineering
|
|
Fluorescent Genetically Encoded Mechanosensors (fGEMs) for Measuring Cellular Tension and Screening Mechanotherapeutics
Brief Description
This innovation introduces a genetically encoded fluorescent mechanosensor (fGEM) that reports changes in mechanical tension within living cells as changes in light intensity. By enabling direct visualization of cellular tension dynamics, this technology provides a powerful new approach for studying mechanobiology and for high-throughput...
Published: 1/13/2026
|
Inventor(s): Em Ben Sorum
Keywords(s):
Category(s): Engineering
|
|
Zero-Carbon to Carbon-Negative Infrastructure
Concrete manufacturing is an energy-intensive process, resulting in significant amounts of GHG/CO2 being released into the atmosphere. The use of a variety of technologies designed to lower these emissions, including supplementary cementitious materials (SCM) (e.g., fly ash, slag, silica fume, and other products), lowering kiln operational temperatures,...
Published: 1/13/2026
|
Inventor(s): Islam Mantawy
Keywords(s):
Category(s): Engineering
|
|
The Rowan Digital Cancellation Test (RDCT): A method for detecting cognitive impairment
Worldwide, over 50 million people live with a disease that causes long-term memory loss. By 2050, this number is projected to almost triple to 130 million. Alzheimer’s disease (AD) is the most common form of dementia leading to long-term memory deficiency, afflicting over 17 million adults over the age of 65. Also, it’s the 5th leading cause...
Published: 1/13/2026
|
Inventor(s): Ganesh Baliga, David Libon
Keywords(s):
Category(s): Engineering
|
|
Energy Fishing using Moving Wind Turbine System
Offshore wind turbines are typically fixed devices anchored to the seabed by a foundation. The advantages of a floating offshore system (economic, reusable, deeper water depths) as compared to fixed structures have resulted in increased interest in floating technologies. The major type of floating wind systems in use today are semisubmersible and concrete...
Published: 1/13/2026
|
Inventor(s): Hooman Ghasemi
Keywords(s): Green, sustainability
Category(s): Engineering, Environment, Other
|
|
Injectable hydrogels with independent control over physical properties and bioactive peptide functionalization
Osteoporosis is the most common bone disease that causes low bone mass, bone tissue deterioration, and bone microarchitecture disruption, leading to compromised bone strength and an increased risk of fractures. More than 200 million people have osteoporosis globally, and about 30% of women and 20% of men over 50 will experience an osteoporotic fracture...
Published: 1/13/2026
|
Inventor(s): Sebastián Vega, Kirstene Giddings, Tae Won Kim
Keywords(s):
Category(s): Engineering
|
|
Distributed Space Computing Framework
Satellites are essential to global communications systems because they can receive and transmit a wide range of data and information. Since they operate in space, satellites can communicate and collect data virtually anywhere without being hindered by terrestrial coverage limitations. Thus, they can cover large sections of the Earth’s surface,...
Published: 1/13/2026
|
Inventor(s): Dwaipayan Chakraborty, Russell Trafford
Keywords(s):
Category(s): Engineering
|
|
Assembly of Polymer Staple Nanofiber Yarns
Nanofiber usage/production has increased in recent years as a result of this materials superior mechanical/strength properties with the primary fabrication technique being electrospinning. Nanofibers can be assembled into highly ordered yarns through twisting of individual nanofibers to form a more durable material, increasing the materials surface...
Published: 1/13/2026
|
Inventor(s): Vincent Beachley
Keywords(s):
Category(s): Engineering
|
