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Development of genetically engineered probes for calcium sensing and manipulation
Calcium levels in cells have critical functions. Moreover, calcium signaling plays a crucial role in the control of neuronal function and plasticity. Consequently, calcium sensing dysfunction can lead to a variety of pathological conditions such as Alzheimer’s disease or neuromuscular disorders such as Dystonia. Changes in neuronal Ca2+ concentration...
Published: 3/4/2024   |   Inventor(s): Venkat Venkataraman, Anuradha Krishnan, Jeffrey Viviano, Jingyi Zhang
Keywords(s): Alzheimer's, Calcium, Genetics, Neurology, Neuromuscular
Category(s): Human Health Care > Therapeutics
Neuropsychological digital assessment test that identifies discrete latencies in response time to identify emergent neurological/nueropsychiatric illness
TechnologyDeclining cognitive health is increasing in the U.S and worldwide. Early detection of impairment is crucial to altering the course of disease. Many cognitive assessments have previously focused on early memory defects, such as those associated with Alzheimer’s, and it is now evident that focused deficits accumulate over several decades...
Published: 3/6/2024   |   Inventor(s): David Libon, Ganesh Baliga, Mary Kerwin, Rod Swenson
Keywords(s): Alzheimer's, Assesments, Cognition, Dementia, Intervention, Neurodegeneration, Quantitative
Category(s): Research Tools, Software, Human Health Care > Biomarkers, Diagnosis and Detection