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Self-forming in vivo dosimeter for radiation therapy verification
Radiation therapy (RT) is one of the most common treatment modalities for cancer and is used in approximately 50% of all treatment plans. It's estimated that RT is responsible for more than 3.5 million successful treatment outcomes along with another 3.5 million for palliative care. Although RT effectively kills cancer, it can cause damage...
Published: 2/5/2024
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Inventor(s): Sebastián Vega, Kirstene Gultian, Leonard Kim, Irina Malajovich, Geoffrey Ibbott
Keywords(s): Dosimetry, Drug Delivery, Hydrogels, Radiation Therapy, Radiotherapy
Category(s): Engineering, Human Health Care > Biomarkers, Diagnosis and Detection
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Multi-material 3D bioprinter for use in drug testing/screening supporting cancer drug discovery.
Cancer testing/screening procedures used in developing new drug therapies take years and are founded on the use of 2D cell cultures and animal models prior to human trials. This pathway is not always representative of how a drug will perform in humans since 2D technology cannot print multi-material bio-cell structures for evaluating new drug performance....
Published: 3/7/2024
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Inventor(s): Amir Miri Ramsheh
Keywords(s): 3D, Cancer, Drug Screening, Hydrogels, Medical Devices
Category(s): Human Health Care > Biomarkers, Diagnosis and Detection, Research Tools
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Self-oxygen generating biomaterials for large tissue engineering
Organ transplantation continues to increase, with 34,770 transplants performed in the US in 2017. Currently, organ transplantation is limited by donor dependence, high costs, and, long-term use of immunosuppressive medications which, in turn, correlates with significant morbidity and mortality. To overcome these limitations, tissue engineering and transplantation...
Published: 3/5/2024
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Inventor(s): Iman Noshadi
Keywords(s): Biomaterials, Electrolyte, Energy Storage, Hydrogels, Oxygenation, Regenerative Medicine, Scaffold, Stem Cells, Tissue Engineering , Transplant
Category(s): Human Health Care > Biomaterials
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A novel sealant device that aids in stem cell localization
in the treatment of lower back pain
TechnologyOne of the major causes of lower back pain is intervertebral disc (IVD) degeneration also known as lumbar degenerative disc disease which often leads to disk herniation. IVD results from the dehydration of the central nucleus pulposus (NP) which ultimately alters the biomechanics of the disc and eventually causes tears to form in the peripheral...
Published: 2/7/2024
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Inventor(s): Andrea Vernengo, Thomas Christiani, Cristina Iftode, Jennifer Kadlowec
Keywords(s): Back Pain, Biomaterials, Hydrogels, Implant, Polymers, Stem Cells, Tissue Engineering
Category(s): Human Health Care > Biomaterials, Human Health Care > Medical Devices, Human Health Care > Therapeutics
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Poly (ionic liquid) surgical and tissue adhesive
TechnologyThis is a new method to improve the adhesion properties of any biomaterial. This method is very general and applicable with wide range of materials. This method is simple and easy to use. Dr. Iman Noshadi in the Department of Chemical Engineering has developed a modified hydrogel to make antimicrobial, highly adhesive for surgical applications....
Published: 3/5/2024
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Inventor(s): Iman Noshadi
Keywords(s): Adhesive, Antimicrobial, Hydrogels, Surgical, Tissue Engineering
Category(s): Human Health Care > Biomaterials
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A novel composition for bioadhesive tissue engineering
Technology
Tissue engineering focuses on repairing or regenerating lost or damaged tissues and organs in the body. A goal of tissue engineering is to design biomimetic scaffolds that reproduce the mechanical and biochemical properties of natural tissue. These scaffolds should have desirable biological properties such that after implantation or application...
Published: 3/6/2024
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Inventor(s): Andrea Vernengo, Jennifer Kadlowec, Pamela Kubinski, Thomas Tulenko, Cristina Iftode, Bryan Johnson, Craig Wiltsey
Keywords(s): Biomaterials, Hydrogels, Polymers, Regenerative Medicine, Scaffold, Stem Cells, Tissue Engineering
Category(s): Human Health Care > Biomaterials, Human Health Care > Medical Devices
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